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[Gastroesophageal reflux disease].

A Arín1, M R Iglesias

  • 1Servicio de Digestivo, Hospital de Navarra, 31008 Pamplona, Spain. aarinlet@cfavarra.es

Anales Del Sistema Sanitario De Navarra
|September 3, 2003
PubMed
Summary

Gastro-oesophageal reflux disease (GERD) is common in the West. Advances in functional testing have improved understanding of GERD

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Area of Science:

  • Gastroenterology
  • Digestive Diseases
  • Clinical Medicine

Context:

  • Gastro-oesophageal reflux disease (GERD) is a highly prevalent condition in Western populations.
  • Understanding GERD's pathophysiology has advanced significantly.
  • Functional diagnostic tools have been crucial in this progress.

Purpose:

  • To review the current understanding of gastro-oesophageal reflux disease (GERD).
  • To examine advancements in the pathogeny, diagnosis, and treatment of GERD.
  • To provide an updated overview of GERD management strategies.

Summary:

  • This review covers the epidemiology and pathophysiology of GERD, highlighting the role of functional explorations like esophageal manometry and 24-hour pH-manometry.
  • It details both typical and atypical clinical presentations of GERD and updates diagnostic methodologies.
  • Current therapeutic options, including pharmacological, endoscopic, and surgical treatments, are comprehensively reviewed.

Impact:

  • Improved understanding of GERD pathophysiology aids in developing targeted therapies.
  • Updated diagnostic approaches enhance accurate GERD identification.
  • Comprehensive review of treatment modalities supports evidence-based clinical decision-making for GERD management.

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