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Recent advances in automated solid-phase carbohydrate synthesis: from screening to vaccines
Obadiah J Plante1, Peter H Seeberger
1Ancora Pharmaceuticals, 100 Cummings Center, Suite 419E, Beverly, MA 01915, USA. oplante@ancorapharma.com
Abstract:
The past year has witnessed significant advances in a new technology for the synthesis of complex carbohydrates. Solid-phase methods have been applied to the construction of previously inaccessible carbohydrates. Furthermore, the application of automated solid-phase carbohydrate synthesis is promising. New methods for the synthesis of carbohydrates and potential applications are described in this review.