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Peculiar pattern of nail pigmentation following cyclophosphamide therapy
Shriya Dave1, Devinder M Thappa
1Department of Dermatology and STD, JIPMER, Pondicherry, India.
Dermatology Online Journal
|September 4, 2003
Abstract:
Cyclophosphamide is one of several cancer chemotherapy agents that can cause nail hyperpigmentation. We report a patient who began to have an unusual form of nail pigmentation after 8 months of receiving monthly pulses of dexamethasone-cyclophosphamide. The patient developed nail pigmentation that started proximally and spread distally but involved only the nails of the thumb, index finger, and half the middle finger of both hands.