Investigating C. elegans development through mosaic analysis
Related Experiment Video
Updated: Sep 20, 2026
Tracking and Quantifying Developmental Processes in C. elegans Using Open-source Tools
Published on: December 16, 2015
1Department of Genetics, Cell Biology and Development, University of Minnesota, 6-160 Jackson Hall, 321 Church Street, Minneapolis, MN 55455, USA.
Abstract:
The analysis of genetically mosaic worms, in which some cells carry a wild-type gene and others are homozygous mutant, can reveal where in the animal a gene acts to prevent the appearance of a mutant phenotype. In this primer article, we describe how Caenorhabditis elegans genetic mosaics are generated, identified and analyzed, and we discuss examples in which the analysis of mosaic worms has provided important information about the development of this organism.
