Related Experiment Video
Updated: Aug 11, 2026

Isolation and Characterization of Dendritic Cells and Macrophages from the Mouse Intestine
Published on: May 21, 2012
Come forth CD1d: Hsp110 in the regulation of intestinal epithelial CD1d expression
1Department of Cell Biology, Duke University Medical Center, Durham, North Carolina 27710, USA. c.nicchitta@cellbio.duke.edu
Abstract:
CD1d, a nonclassical MHC class I-like molecule, is prominently expressed on intestinal epithelial cells and is thought to function in the regulation of intestinal intraepithelial lymphocyte activity. Hsp110, an abundant heat shock protein present in essentially all mammalian tissues, has now been shown to upregulate CD1d expression in colonic tissue culture cell lines. Might this abundant chaperone serve an autocrine function in the regulation of CD1d expression?
More Related Videos
Related Concept Videos
Renewal of Intestinal Stem Cells
Role of Ephrin-Eph Signalling in Intestinal Stem Cell Renewal
Role Of Notch Signalling In Intestinal Stem Cell Renewal
Direct cell-to-cell contact is needed for the activation of Notch signaling. The signal is initiated when a notch ligand binds to a receptor on an adjacent cell, also...
Inflammatory Bowel Disease III: Crohn's Disease

