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Successful pregnancy in a woman with congenital "Swiss-cheese" platelets. A case report
Louis Yik-Si Chan1, Tse Ngong Leung
1Department of Obstetrics and Gynaecology, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong. lyschan@cuhk.edu.hk
Background:
Congenital "Swiss-cheese" platelets are a rare disorder of platelet function due to impaired calcium mobilization. Management of pregnancy in patients with this disorder had not been reported previously.
Case:
Successful pregnancy occurred in a woman with congenital Swiss-cheese platelets. Neither the mother nor neonate experienced any hemorrhagic complications.
Conclusion:
Successful pregnancy is possible in women with congenital Swiss-cheese platelets. The lack of hemorrhagic complications may be due to the increase in platelet intracellular free calcium concentration during pregnancy.