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PROGRESS results: implementation in stroke guidelines
1National Stroke Research Institute, West Heidelberg, Victoria, Australia. gdonnan@unimelb.edu.au
Summary
Implementing evidence from the Perindopril pROtection aGainst REcurrent Stroke Study (PROGRESS) is crucial for secondary stroke prevention. Minimal barriers exist, supporting blood pressure lowering as a key strategy.
Area of Science:
- Clinical medicine
- Cardiovascular research
- Neurology
Background:
- Transferring clinical trial evidence into practice is a significant challenge for healthcare providers.
- Physician, patient, and community acceptance are vital for successful evidence implementation.
- The Perindopril pROtection aGainst REcurrent Stroke Study (PROGRESS) provides critical data for stroke prevention.
Purpose of the Study:
- To assess the ease of transferring evidence from the PROGRESS study into clinical practice.
- To determine the potential impact of PROGRESS findings on secondary stroke prevention strategies.
Main Methods:
- Analysis of barriers to the implementation of PROGRESS study findings.
- Evaluation of the components necessary for successful evidence transfer in stroke prevention.
Main Results:
- Minimal barriers were identified for the transfer of evidence from the PROGRESS study into clinical practice.
- Physician, patient, and community acceptance factors appear favorable for implementing PROGRESS findings.
Conclusions:
- The evidence from the PROGRESS study can be readily transferred into clinical practice.
- Blood pressure lowering should be established as the fourth major secondary prevention strategy for stroke based on the PROGRESS findings.