Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

secureBLAST.

Arnim Wiezer1, Rainer Merkl

  • 1Goettingen Genomics Laboratory, Institut fuer Mikrobiologie and Genetik, Grisebachstrasse 8, D-37077 Goettingen, Germany.

In Silico Biology
|September 5, 2003
PubMed
Summary
This summary is machine-generated.

secureBLAST enhances NCBI BLAST by enabling controlled access to datasets on a single server. This secure web-based administration is ideal for institutions needing to manage user permissions and data updates efficiently.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Experimental and computational analysis of the ancestry of an evolutionary young enzyme from histidine biosynthesis.

Protein science : a publication of the Protein Society·2022
Same author

Multivalent display of engineered HIV-1 envelope trimers on silica nanoparticles for targeting and in vitro activation of germline VRC01 B cells.

European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V·2022
Same author

Rosetta:MSF:NN: Boosting performance of multi-state computational protein design with a neural network.

PloS one·2021
Same author

Evidence for the preferential reuse of sub-domain motifs in primordial protein folds.

Proteins·2021
Same author

Rosetta design with co-evolutionary information retains protein function.

PLoS computational biology·2021
Same author

Sequence and functional differences in the ATPase domains of CHD3 and SNF2H promise potential for selective regulability and drugability.

The FEBS journal·2021
Same journal

Regulatory Effects of Cooperativity and Signal Profile on Adaptive Dynamics in Incoherent Feedforward Loop Networks.

In silico biology·2025
Same journal

scAN1.0: A reproducible and standardized pipeline for processing 10X single cell RNAseq data.

In silico biology·2023
Same journal

Modelling speciation: Problems and implications.

In silico biology·2022
Same journal

Where Do CABs Exist? Verification of a specific region containing concave Actin Bundles (CABs) in a 3-Dimensional confocal image.

In silico biology·2022
Same journal

Network analysis of host-pathogen protein interactions in microbe induced cardiovascular diseases.

In silico biology·2022
Same journal

Multiscale modeling of tumor response to vascular endothelial growth factor (VEGF) inhibitor.

In silico biology·2022
See all related articles

Area of Science:

  • Bioinformatics
  • Computational Biology
  • Genomic Data Management

Background:

  • National Center for Biotechnology Information (NCBI) BLAST is a widely used tool for sequence similarity searching.
  • Managing access and updates for multiple BLAST datasets on a single server presents administrative challenges.
  • Existing BLAST implementations may lack granular control over data access and user permissions.

Purpose of the Study:

  • To introduce secureBLAST, a system designed to enhance the functionality of NCBI BLAST.
  • To provide a secure and manageable solution for controlling access to BLAST datasets.
  • To enable efficient administration of BLAST servers and associated databases via a web interface.

Main Methods:

  • Implementation of a system that allows multiple datasets on a single BLAST server.

Related Experiment Videos

  • Configuration of individually controllable access rights for each dataset.
  • Integration of user authentication and Secure Sockets Layer (SSL) encryption for secure HTTP traffic.
  • Development of a web interface for streamlined administration of users and databases.

    • Main Results:

    • secureBLAST successfully supplements NCBI BLAST with robust access control features.
    • The system allows for the hosting of diverse datasets with distinct access privileges on one server.
    • User and database administration is simplified through an intuitive web interface.
    • Secure data transfer is ensured via SSL encryption.

    Conclusions:

    • secureBLAST offers a valuable solution for institutions requiring restricted access to their BLAST datasets.
    • The system simplifies the administration of BLAST servers, enhancing usability and security.
    • It provides a centralized platform for managing user permissions and data updates efficiently.
    • secureBLAST is particularly beneficial for organizations with sensitive genomic data or complex access requirements.