Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Hepatitis C and B-cell lymphoma.

N C Turner1, G Dusheiko, A Jones

  • 1Department of Clinical Oncology and Centre for Hepatology, Royal Free and University College Medical School, London, UK.

Annals of Oncology : Official Journal of the European Society for Medical Oncology
|September 5, 2003
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

IncC of broad-host-range plasmid RK2 modulates KorB transcriptional repressor activity In vivo and operator binding in vitro.

Journal of bacteriology·1999
Same author

'Listen, listen trust your own strange voice' (psychoanalytically informed conversations with a woman suffering serious illness).

Journal of advanced nursing·1999
Same author

p53 and p53-regulated genes in bladder cancer.

BJU international·1999
Same author

Angiogenesis in urological malignancy: prognostic indicator and therapeutic target.

BJU international·1999
Same author

Functional genomics in Caenorhabditis elegans: An approach involving comparisons of sequences from related nematodes.

Genome research·1999
Same author

Directed evolution of a fungal peroxidase.

Nature biotechnology·1999

The link between hepatitis C virus (HCV) and B-cell non-Hodgkin's lymphoma (NHL) is debated. Antiviral therapy for HCV may help some lymphomas regress, but others require standard treatment with potential complications.

Area of Science:

  • Hepatology
  • Oncology
  • Virology

Background:

  • The association between hepatitis C virus (HCV) infection and B-cell non-Hodgkin's lymphoma (NHL) remains a subject of scientific debate.
  • Variations in study findings necessitate a review of epidemiological evidence and potential pathogenetic links.

Purpose of the Study:

  • To critically evaluate the epidemiological evidence supporting the association between HCV and B-cell NHL.
  • To explore the pathogenetic mechanisms linking HCV to lymphoma development.
  • To discuss the implications for clinical management and treatment outcomes.

Main Methods:

  • Systematic review of epidemiological studies investigating HCV and NHL.
  • Analysis of pathogenetic data concerning viral-induced lymphomagenesis.

Related Experiment Videos

  • Review of clinical management strategies and treatment responses.

    • Main Results:

    • Increasing evidence supports a pathogenetic role for HCV in certain lymphomas.
    • Antiviral therapy targeting HCV has shown potential for inducing regression in some low-grade lymphomas.
    • Management of other HCV-associated lymphomas aligns with conventional approaches, but complications like viral reactivation must be considered.

    Conclusions:

    • HCV is increasingly recognized as a contributing factor in the pathogenesis of specific B-cell lymphomas.
    • HCV treatment offers a potential therapeutic avenue for certain HCV-associated lymphomas.
    • Clinical management requires careful consideration of viral dynamics and potential treatment complications.