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Membrane-associated CD40L and sCD40L in atherothrombotic disease
Sunil X Anand1, Juan F Viles-Gonzalez, Juan J Badimon
1The Zena and Michael A. Weiner Cardiovascular Institute, Mount Sinai School of Medicine, New York, New York. USA.
Thrombosis and Haemostasis
|September 6, 2003
Abstract:
Recent data suggests that CD40L is involved in the pathogenesis of atherothrombotic disease. This review will focus on the history of CD40L, its role in platelet-mediated pathogenesis of atherothrombotic disease, its association to clinical syndromes and procedures, and its role in determining plaque rupture.