Related Experiment Videos
Relationship between cholecystolithiasis and polypoid gallbladder
Ai-jiao Wu1, Ying-qi Li, Li-an Du
1Zhejiang University Hospital, 310027 Hangzhou, China. wuaijiang1231@sina.com
Objective:
To study the relationship between cholecystolithiasis and polypoid gallbladder (PLG), 260 patients with polypoid gallbladder were investigated. The patients were divided into 2 groups: group A (PLG combined with cholecystolithiasis) and group B (without cholecystolithiasis). The clinical pathological characteristics were analyzed. The intestinal epithelium metaplasia and atypical hyperplasia of the gallbladder mucosa were observed under light microscope.
Results:
Intestinal epithelium metaplasia and atypical hyperplasia of gallbladder mucosa were found in 47 of the 260 cases. The pathological lesions included 16 gallbladder carcinoma, 11 adenomatosis polyp, 5 myoadenoma, 7 cholesterol polyp, 4 inflammatory polyp and 4 adenomatosis hyperplasia, which occurred in 26 and 21 patients in group A and group B, i.e. 44.0% and 10.3% respectively. The difference between group A and group B was statistically significant (P<0.01).
Conclusion:
Cholecystolithiasis and the succeeding inflammatory reaction is a risk-factor for the polypoid gallbladder to develop tumour.