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Establishment of an Oronasal Fistula Mice Model
Published on: September 8, 2023
[Clinical study on fistula incidence of early cleft palate repair]
1Guangzhou Children's Hospital, Guangzhou 510120, China.
Insights
Early cleft palate repair in infants does not increase fistula incidence. Bilateral cleft palate cases show a higher fistula rate, suggesting preoperative orthodontics may be beneficial.
Area of Science:
- Craniofacial surgery
- Pediatric surgery
- Plastic surgery
Background:
- Cleft palate repair is a common surgical procedure in infants.
- Fistula formation is a potential complication following cleft palate repair.
- Understanding fistula incidence patterns is crucial for optimizing surgical outcomes.
Purpose of the Study:
- To investigate the incidence and patterns of fistula formation after early cleft palate repair.
- To identify risk factors associated with fistula development in this patient population.
Main Methods:
- Retrospective analysis of 531 patients aged 2-12 months who underwent cleft palate repair between July 1995 and September 2001.
- Data collection included patient demographics, cleft type, surgical technique, and fistula occurrence.
Main Results:
- The overall fistula incidence was 4.9%.
- Bilateral complete cleft palate had a significantly higher fistula incidence (7.8%) compared to incomplete (4.4%) and unilateral complete cleft palate (4.3%).
- Fistula location was most common on the hard palate in complete cleft palate cases (70%). Patient age and surgical method did not significantly impact fistula incidence.
Conclusions:
- Early cleft palate repair in infants is not associated with an increased risk of fistula formation.
- Preoperative orthodontics is recommended for infants with bilateral cleft palate to potentially reduce fistula rates.
Objective:
To study the regularity of fistula incidence after early cleft palate repair
Methods:
531 patients aged 2-12 months at the operation were included in the retrospective study, who underwent cleft palate repair during July 1995 to September 2001.
Results:
The overall frequency of fistulas was 4.9%. The fistula incidence of bilateral complete cleft palate was obviously higher (7.8%) than that of incomplete cleft palate (4.4%) and the unilateral complete group (4.3%) (P < 0.005). There was no significant difference between the latter two. Fistula incidence was irrelevant to the patient age and the operation method. Seventy percent of fistulas in complete cleft palate occurred on the hard palate, which was significantly higher than that on the other parts.
Conclusion:
Infant cleft palate repair did not increase fistula incidence. We recommend preoperative orthodontics for bilateral cleft palate infants.
