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Maximal lactate steady state declines during the aging process.

Craig O Mattern1, Margaret J Gutilla, Darrin L Bright

  • 1Sport and Exercise Science Program, The Ohio State University, Columbus, OH 43210-1284, USA.

Journal of Applied Physiology (Bethesda, Md. : 1985)
|September 10, 2003
PubMed
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Older athletes experience a decline in maximal lactate steady-state (MLSS) exercise intensity, even when matched for training. This age-related decrease in MLSS intensity impacts athletic performance in aging individuals.

Area of Science:

  • Exercise Physiology
  • Sports Science
  • Aging Research

Background:

  • Growing participation of older adults in athletics necessitates research into age-related performance changes.
  • Potential age-related declines in aerobic enzyme activity and myosin heavy chain (MHC) isoform expression may affect exercise intensity.
  • Maximal lactate steady-state (MLSS) is a key indicator of endurance exercise intensity.

Purpose of the Study:

  • To investigate age-related alterations in maximal lactate steady-state (MLSS) exercise intensity among competitive male athletes.
  • To test the hypothesis that MLSS exercise intensity declines with age due to changes in aerobic enzymes and MHC isoforms.

Main Methods:

  • Study included three groups of male athletes: young (YA), middle-age (MA), and older (OA), matched for training.

Related Experiment Videos

  • Maximal oxygen consumption (VO2 max) tests and 30-minute exercise trials to determine MLSS were conducted.
  • Muscle biopsies were analyzed for citrate synthase activity and MHC isoform profiles.

    • Main Results:

    • VO2 max significantly decreased across age groups (YA > MA > OA).
    • Relative MLSS exercise intensity also showed a significant age-related decline (YA > MA > OA).
    • No significant age-related changes were observed in citrate synthase activity or MHC isoform profiles.

    Conclusions:

    • The hypothesis is supported: MLSS exercise intensity declines with age in trained male athletes.
    • Age-related decline in MLSS intensity occurs independently of changes in citrate synthase or MHC isoform expression.
    • While MHC isoform type I and age can predict relative MLSS intensity, they do not fully explain the age-related decrease.