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Updated: Aug 6, 2026

Monitoring Functionality and Morphology of Vasculature Recruited by Factors Secreted by Fast-growing Tumor-generating Cells
Published on: November 23, 2014
Anti-angiogenesis in cancer therapy
1Clinical Center Nursing Department, National Institutes of Health, Bethesda, MD, USA.
Objective:
To review tumor angiogenesis, identify potential targets for anti-angiogenic cancer therapy, and highlight certain anti-angiogenic agents in clinical trials.
Data Source:
Research articles, abstracts, review articles, and book chapters.
Conclusion:
Tumor angiogenesis is a complex, multistep process that provides a target for antineoplastic therapy whereby tumor neovasculature is interrupted at various steps in the angiogenic process. Clinical trials are investigating the application and efficacy of anti-angiogenic agents.
Implications For Nursing Practice:
Oncology nurses must continually increase their knowledge with the onset of newer, targeted agents. This will provide a background for educating and caring for the patient who is receiving anti-angiogenic therapy.
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