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Related Experiment Videos

[Therapeutic apheresis in multiple sclerosis].

Kyoichi Nomura1

  • 1Department of Neurology, Saitama Medical School.

Nihon Rinsho. Japanese Journal of Clinical Medicine
|September 10, 2003
PubMed
Summary

Plasmapheresis (PP) effectively removes immune factors in multiple sclerosis (MS). While plasma exchange (PE) helps acute MS, immunoadsorption plasmapheresis (IAPP) may offer superior treatment for MS patients.

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Area of Science:

  • Neurology
  • Immunology
  • Medical Technology

Context:

  • Therapeutic apheresis, including plasmapheresis (PP), is crucial for neuroimmunological disorders.
  • PP encompasses plasma exchange (PE), double filtration plasmapheresis (DFPP), and immunoadsorption plasmapheresis (IAPP).

Purpose:

  • To review the application and effectiveness of plasmapheresis (PP) in treating multiple sclerosis (MS).

Summary:

  • PP removes pathogenic immune factors like autoantibodies and cytokines, impacting both humoral and cellular immunity.
  • Plasma exchange (PE) shows efficacy in acute MS attacks but not chronic progressive MS.
  • Immunoadsorption plasmapheresis (IAPP) may be more effective than PE for MS treatment.

Impact:

  • Highlights the potential of specific PP techniques, particularly IAPP, in managing MS.
  • Informs clinical decisions regarding apheresis strategies for multiple sclerosis patients.

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