Related Experiment Video
Updated: Sep 20, 2026

Cardiac Magnetic Resonance for the Evaluation of Suspected Cardiac Thrombus: Conventional and Emerging Techniques
Published on: June 11, 2019
Floating ball thrombus in the left atrium with mitral stenosis
Takahiko Misumi1, Mikihiko Kudo, Tsutomu Ito
1Division of Cardiovascular Surgery, Hiratsuka City Hospital, Hiratsuka, Kanagawa, Japan.
Insights
A rare case of a floating ball thrombus in the left atrium causing cerebral infarction is presented. This unusual cardiac thrombus required surgical removal and mitral valve replacement.
Area of Science:
- Cardiology
- Cardiovascular Surgery
- Neurology
Background:
- Mitral stenosis is a common valvular heart disease.
- Atrial fibrillation and left atrial mural thrombi are known complications of mitral stenosis.
- Cerebral infarction can be caused by cardioembolic events.
Observation:
- A 76-year-old woman with a history of mitral stenosis presented with right cerebral infarction.
- Echocardiography revealed a mobile, spherical thrombus (30x30x30 mm) in the left atrium.
- The patient also had atrial fibrillation and a pre-existing left atrial mural thrombus.
Findings:
- The left atrial ball thrombus was surgically removed concurrently with mitral valve replacement.
- The thrombus was described as single, round, soft, and smooth-surfaced.
- Postoperative recovery was uneventful.
Implications:
- Left atrial ball thrombi are uncommon but pose a significant embolic risk.
- This case highlights the potential for mural thrombi to embolize and form mobile ball thrombi.
- Prompt diagnosis and surgical intervention are crucial for managing such rare cardiac emergencies.
Abstract:
We report a case of a floating ball thrombus in the left atrium with mitral stenosis in a 76-year-old woman. The patient had been followed-up at our hospital due to mitral valve stenosis for several years, and was recognized to have atrial fibrillation and a left atrial mural thrombus by echocardiography. She was admitted to our hospital for right cerebral infarction. Echocardiography showed a floating ball thrombus in the left atrium. After the treatment of cerebral infarction, she was referred to cardiac surgery, and a semi-urgent operation was performed. Removal of the ball thrombus and mitral valve replacement were performed simultaneously. The thrombus was single, round, soft, relatively smooth surfaced, and about 30 x 30 x 30 mm in diameter. The postoperative course was uneventful. Left atrial ball thrombus appears to be uncommon. This is a rare case, in which it was documented that a pre-existing left atrial mural thrombus was thought to drop off spontaneously, to be a cerebral embolic source, and to develop into a ball thrombus in the left atrium.
Related Concept Videos
Mitral Stenosis I: Introduction
Mitral Stenosis II: Clinical features and Diagnostic Tests
Mitral Regurgitation II: Clinical Features and Diagnostic Tests
Mitral Valve Prolapse I: Introduction
Mitral Stenosis III: Medical Management
Mitral Regurgitation I: Introduction