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Benign nodular lymphoid hyperplasia of colon: a report of two cases

Suresh Chandra1

  • 1Manipal Hospital, Bangalore. suresh_sudha@vsnl.com

Indian Journal of Gastroenterology : Official Journal of the Indian Society of Gastroenterology
|September 10, 2003
PubMed

Insights

Benign nodular lymphoid hyperplasia of the colon is a rare condition in children that can cause intestinal obstruction. This entity must be distinguished from malignant lymphomas.

Area of Science:

  • Pediatric Gastroenterology
  • Surgical Pathology

Background:

  • Benign nodular lymphoid hyperplasia (BNLH) of the colon is a rare condition in children.
  • It is crucial to differentiate BNLH from lymphoid polyps and malignant lymphomas.
  • The etiology of BNLH in pediatric patients remains unclear.

Observation:

  • This report details two pediatric cases (9 and 5 years old) presenting with intestinal obstruction due to BNLH.
  • No specific etiologic cause was identified in either patient.
  • Immunochemistry using Pan B and Pan T markers revealed expected staining patterns within the lymphoid aggregates in one case.

Findings:

  • Nodular lymphoid hyperplasia of the colon can lead to significant clinical manifestations like intestinal obstruction in children.
  • Immunohistochemical analysis supports the benign nature of the lymphoid aggregates.
  • Further investigations, including viral marker studies, were not performed in these cases.

Implications:

  • Accurate differentiation of BNLH from colonic lymphomas is critical for appropriate patient management.
  • Surgical resection was the chosen intervention for intestinal obstruction caused by BNLH.
  • This case report highlights the importance of considering rare benign conditions in the pediatric differential diagnosis of intestinal obstruction.

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