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Porcine Liver Transplantation Without Veno-Venous Bypass As an Extended Criteria Donor Model
Published on: August 17, 2022
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Outcome of 28 split liver grafts
C Margarit1, M Asensio, J Iglesias
1Liver Transplantation Unit, Hospital Vall Hebrón, Barcelona, Spain. margarit@hg.vhebron.es
Transplantation Proceedings
|September 10, 2003
Summary
Split liver transplantation offers viable grafts for adults and children. While elective cases show good survival, emergency cases have lower survival rates due to patient condition.
Area of Science:
- Hepatobiliary Surgery
- Transplant Surgery
- Pediatric Surgery
Background:
- Split liver transplantation (SLT) is a technique to increase the donor liver pool.
- Ex situ splitting allows for precise graft preparation for adult and pediatric recipients.
Purpose of the Study:
- To present the experience with ex situ split liver transplantation.
- To evaluate outcomes in adult and pediatric recipients, including elective and emergency cases.
Main Methods:
- 14 livers were split ex situ between 1992 and 2002, yielding 28 grafts.
- Grafts were transplanted into 12 adults and 16 children.
- Graft composition varied based on recipient size, with left lateral segments or left lobes used.
Main Results:
- Overall postoperative mortality was 31%, with higher rates in emergency cases (67%) compared to elective cases (10%).
- Technical complications included arterial thrombosis (1), portal vein thrombosis (1), and biliary complications (4).
- One-year actuarial survival was 84%, with 11 patients alive and well at the end of the study period.
Conclusions:
- Split liver transplantation in elective settings yields results comparable to whole liver transplantation.
- Patient survival in emergency SLT is limited by the recipients' critical preoperative status.
