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Updated: Sep 20, 2026
Mouse Model of Alloimmune-induced Vascular Rejection and Transplant Arteriosclerosis
Published on: May 17, 2015
Results of percutaneous revascularization in cardiac allograft vascular disease
J Fernández-Yáñez1, J Palomo, J Elízaga
1Cardiology Department, Hospital General Universitario Gregorio Marañón, Madrid, Spain.
Objectives:
To evaluate the outcome of transplant patients with CGD treated by PTCA in our center.
Methods:
We retrospectively analyzed the medical records of all PTCA procedures performed on heart transplant patients in our hospital.
Results:
Among 13 patients (11 men, 52.9+/-9.7 years), 20 lesions were treated with PTCA with 95% initial angiographic success. The indications for PTCA was heart failure or ventricular systolic dysfunction (n=4), of ischemia (n=4) and angiographic criteria alone (n=5). Ten lesions were treated with balloon angioplasty. A stent was implanted in 10 lesions, including one patient with a previous atherectomy. There were no complications. Angiographic follow-up was performed on 11 patients, four of whom (36%) showed restenosis. Mean follow-up was 33 months. Four patients (30.8%) are alive without retransplantation, two (15.4%) are alive after retransplantation, and seven (53.4%) died, all from cardiac causes. Graft survival rates estimated by the Kaplan-Meier method were 62% in the first year and 46% in the second year.
Conclusions:
Our results suggest that PTCA represents a palliative method of treatment for heart transplant patients with CGD.
