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Published on: February 14, 2017
Can progression of valvar aortic stenosis be predicted accurately?
Cornelia Piper1, Rito Bergemann, Hagen D Schulte
1Department of Cardiology, Heart Center North Rhine-Westphalia, Ruhr University of Bochum, Bad Oeynhausen, Germany. cpiper@hdz-nrw.de
Insights
Predicting the progression of aortic stenosis is possible using aortic valve opening area and calcification degree. This helps in planning timely cardiac surgery for patients with aortic stenosis.
Area of Science:
- Cardiology
- Cardiac Surgery
- Valvular Heart Disease
Background:
- Aortic stenosis progression assessment is crucial for surgical timing.
- Past therapeutic planning often overlooked progression, leading to reoperations.
- Developing criteria for rapid hemodynamic progression is essential.
Purpose of the Study:
- To establish criteria for assessing rapid hemodynamic progression of valvar aortic stenosis.
- To aid in therapeutic planning for patients requiring cardiac surgery for other reasons.
- To prevent premature cardiac reoperations due to unfulfilled aortic valve replacement criteria.
Main Methods:
- Analysis of hemodynamic, echocardiographic, and clinical data from 257 patients.
- Inclusion of data from initial and follow-up cardiac catheterizations.
- Assessment of patient demographics including age and sex.
Main Results:
- Progression rate correlated exponentially with initial aortic valve opening area (AVA) and valvar calcification (VC) score.
- Neither patient age, sex, nor etiology significantly impacted stenosis progression.
- Specific AVA and VC thresholds predict future need for aortic valve replacement.
Conclusions:
- Aortic valve opening area and valvar calcification degree sufficiently predict asymptomatic aortic stenosis progression.
- These parameters are valuable for clinical decision-making and surgical planning.
- Proactive assessment can optimize patient outcomes and reduce reoperation rates.
Background:
It was the aim of the present study to elaborate criteria for the assessment of rapid hemodynamic progression of valvar aortic stenosis. These criteria are of special importance when cardiac surgery is indicated for other reasons but the established criteria for aortic valve replacement are not yet fulfilled. Such aspects of therapeutic planing were mostly disregarded in the past so that patients had to undergo cardiac reoperation within a few years.
Methods:
Hemodynamic, echocardiographic, and clinical data of 169 men and 88 women with aortic stenosis, aged 55.2 +/- 15.7 years at their first and 63.4 +/- 15.6 years at their second cardiac catheterization, were analyzed.
Results:
The progression rate of aortic valve obstruction was found to be dependent on the degree of valvar calcification ([VC] scoring 0 to III) and to be exponentially correlated with the aortic valve opening area (AVA) at initial catheterization. Neither age nor sex of the patient nor etiology of the valvar obstruction significantly influence the progression of aortic stenosis. If AVA decreases below 0.75 cm(2) with a present degree of VC = 0, or AVA of 0.8 with VC of I, AVA of 0.9 with VC of II, or AVA of 1.0 with VC of III, it is probable that aortic stenosis will have to be operated upon in the following years.
Conclusions:
The present data indicate that for clinical purposes and planning of valvar surgery the progression of asymptomatic aortic stenosis can be sufficiently predicted by the present aortic valve opening area and the degree of valvar calcification.
Related Concept Videos
Mitral Stenosis I: Introduction
Mitral Stenosis II: Clinical features and Diagnostic Tests
Aortic Regurgitation I: Introduction
Aortic Regurgitation II: Clinical Features and Diagnostic Tests
Aortic Regurgitation III: Medical Management

