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Pulmonary autografts in patients with severe left ventricular dysfunction
Stephen C Gauthier1, Joshua G Barton, Mary M Lane
1Section of General Surgery, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma 73190, USA.
The Annals of Thoracic Surgery
|September 10, 2003
Summary
The Ross operation is a safe and effective treatment for aortic valve disease in patients with severe left ventricular dysfunction. This study shows excellent survival and improved heart function after the procedure.
Area of Science:
- Cardiovascular Surgery
- Cardiac Surgery
- Heart Valve Surgery
Background:
- The Ross operation for severe left ventricular dysfunction is debated.
- This study evaluated 15 patients with aortic valve disease and ejection fraction < 40%.
Purpose of the Study:
- To determine the outcome of the Ross operation in patients with reduced left ventricular function.
- To assess survival, clinical status, and cardiac function post-procedure.
Main Methods:
- Retrospective review of 15 patients (age 18-50) with ejection fraction < 40% undergoing the Ross operation.
- Echocardiograms and patient records were analyzed for survival, function, and valve status.
Main Results:
- No operative or late deaths; no reoperations were required.
- 67% of patients showed improved ventricular function, with ejection fraction increasing from 31% to 51%.
- Left ventricular mass index significantly decreased post-operation.
Conclusions:
- The Ross operation is a suitable option for adults up to age 50 with reduced ejection fraction.
- No operative mortality or adverse sequelae were observed.
- Excellent survival and cardiac recovery are anticipated.