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Published on: December 11, 2017
Repair of left ventricular aneurysm: surgical risk and long-term survival
Runar Lundblad1, Michel Abdelnoor, Jan L Svennevig
1Department of Cardiothoracic Surgery, Rikshospitalet, Oslo, Norway. runar.lundblad@rikshospitalet.no
Insights
Predictors for survival after left ventricular aneurysm repair were identified. Advanced age, ventricular arrhythmia, three-vessel disease, and linear repair impact mortality, while poor left ventricular function affects long-term survival.
Area of Science:
- Cardiology
- Cardiac Surgery
- Medical Research
Background:
- Postinfarction left ventricular aneurysm presents a significant clinical challenge.
- Surgical repair is a treatment option, but predictors of patient outcomes require elucidation.
Purpose of the Study:
- To identify predictors of survival following surgical repair of postinfarction left ventricular aneurysm.
- To analyze factors influencing both early and long-term patient survival.
Main Methods:
- Retrospective review of 149 patients undergoing surgical repair between 1989 and 2001.
- Analysis of preoperative clinical, angiographic, and echocardiographic data.
- Statistical methods including logistic regression and Cox regression for risk factor identification.
Main Results:
- Early mortality rate was 8.7%, with a 5-year survival rate of 77%.
- Independent risk factors for mortality included advanced age, ventricular arrhythmia, three-vessel disease, and linear repair technique.
- Poor left ventricular function predicted reduced long-term survival.
Conclusions:
- Surgical repair of postinfarction left ventricular aneurysm is feasible with acceptable risk.
- Survival outcomes are negatively influenced by advanced age, ventricular arrhythmia, three-vessel disease, and specific surgical techniques.
- Identifying these risk factors aids in patient selection and surgical planning.
Background:
The aim of the study was to identify predictors for survival after repair of postinfarction left ventricular aneurysm.
Methods:
We retrospectively reviewed the records of 149 patients who had an operation for postinfarction left ventricular aneurysm between 1989 and 2001. The following variables were recorded: preoperative clinical, angiographic, and echocardiographic findings and operative procedures. Outcomes were early mortality (<30 days) and long-term survival. Risk factors were pinpointed using t test or Mann-Whitney test, contingency tables, and survival curves. Independent risk factors were identified by logistic regression and Cox regression methods. Mean follow-up was 5.8 years (range, 0 to 13.8 years).
Results:
The early mortality (<30 days) rate was 8.7% altogether, and the 5-year cumulative survival rate was 77%. Advanced age, history of ventricular arrhythmia, three-vessel disease, and linear repair technique were independent risk factors for early and total mortality. Poor left ventricular function predicted reduced long-term survival but did not increase surgical risk. Survival was not affected by gender, diabetes, type and severity of symptoms, anterior or posterior aneurysm, revascularization of the left anterior descending artery, or number of distal anastomoses.
Conclusions:
Postinfarction left ventricular aneurysm can be repaired with acceptable surgical risk and long-term survival. Survival is reduced in cases with advanced age, history of ventricular arrhythmia, three-vessel disease, poor left ventricular function, and linear repair of the aneurysm.
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