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Related Experiment Videos

[A case of functional hyperprolactinemia].

J Przybyłowski1, J Siedlecki, E Kapłon

  • 1Oddziału Wewnetrznego Wojewódzkiego Szpitala Zespolonego, Kielcach.

Wiadomosci Lekarskie (Warsaw, Poland : 1960)
|October 1, 1992
PubMed
Summary

Functional hyperprolactinaemia, characterized by high prolactin levels, was diagnosed in a woman with galactorrhoea and amenorrhoea. Treatment with parlodel led to symptom resolution, indicating its efficacy in managing this condition.

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Area of Science:

  • Endocrinology
  • Neuroendocrinology
  • Reproductive Medicine

Background:

  • Functional hyperprolactinaemia can present with symptoms such as galactorrhoea and amenorrhoea.
  • Acute neurosis may coexist with endocrine disorders.
  • Metoclopramide challenge test is a diagnostic tool for hyperprolactinaemia.

Observation:

  • A 27-year-old woman presented with simultaneous galactorrhoea, amenorrhoea, and signs of acute neurosis.
  • Diagnosis of functional hyperprolactinaemia was established via metoclopramide-induced prolactin level determination.
  • Other potential causes of hyperprolactinaemia were systematically excluded.

Findings:

  • Treatment with parlodel resulted in complete regression of the patient's signs and symptoms.
  • Follow-up after 18 months revealed persistent, albeit slightly reduced, elevated prolactin levels post-metoclopramide administration.
  • This case highlights the effectiveness of parlodel in managing functional hyperprolactinaemia.

Implications:

  • Functional hyperprolactinaemia can be effectively managed with dopamine agonist therapy.
  • Long-term monitoring is crucial even after symptom resolution due to potential persistent hormonal abnormalities.
  • Understanding the interplay between neurosis and endocrine dysfunction is important for comprehensive patient care.

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