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[Impaired left ventricular systolic function in mitral stenosis]

Mayumi Shikano1, Satoshi Nakatani, Jiyoong Kim

  • 1Cardiology Division, National Cardiovascular Center, Fujishiro-dai 5-7-1, Suita, Osaka 565-8565.

Journal of Cardiology
|September 11, 2003
PubMed

Insights

Left ventricular dysfunction affects 21% of patients with mitral stenosis. Atrial fibrillation may contribute to reduced left ventricular contraction in these patients.

Area of Science:

  • Cardiology
  • Echocardiography
  • Cardiac Electrophysiology

Background:

  • Left ventricular dysfunction is a known complication of mitral stenosis.
  • The precise incidence and underlying causes of left ventricular dysfunction in mitral stenosis remain incompletely understood.
  • This study focuses on strictly selected patients with isolated mitral stenosis.

Purpose of the Study:

  • To determine the incidence of left ventricular dysfunction in isolated mitral stenosis.
  • To investigate factors associated with left ventricular dysfunction in this patient cohort.

Main Methods:

  • Echocardiography was used to assess left atrial and left ventricular dimensions, mitral valve area, and mean transmitral pressure gradient in 33 patients.
  • Left ventricular ejection fraction was calculated using Simpson's method.
  • Patients were stratified into two groups based on ejection fraction (<50% and >=50%).

Main Results:

  • Left ventricular dysfunction (ejection fraction <50%) was observed in 21% of patients.
  • The incidence of atrial fibrillation was significantly higher in the low ejection fraction group (86%) compared to the normal ejection fraction group (31%, p < 0.01).
  • No significant differences in mitral stenosis severity or other echocardiographic parameters were found between the groups.

Conclusions:

  • A significant proportion (21%) of patients with mitral stenosis exhibit reduced left ventricular ejection fraction.
  • The higher prevalence of atrial fibrillation in patients with low ejection fraction suggests a potential link between this rhythm disturbance and impaired left ventricular contraction.
  • Further research is warranted to elucidate the causal relationship between atrial fibrillation and left ventricular dysfunction in mitral stenosis.
Abstract

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