Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Highly sensitive glucose sensor based on work function changes measured by an EMOSFET.

T V Anh Dam1, D Pijanowska, W Olthuis

  • 1MESA+ Research Institute, University of Twente, P.O. Box 217, 7500AE Enschede, The Netherlands.

The Analyst
|September 11, 2003
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Determining the antioxidant properties of various beverages using staircase voltammetry.

Heliyon·2020
Same author

Microfluidics and catalyst particles.

Lab on a chip·2019
Same author

Survey: interpolation methods for whole slide image processing.

Journal of microscopy·2016
Same author

Solid contact potassium selective electrodes for biomedical applications - a review.

Talanta·2016
Same author

Towards microfluidic sperm refinement: impedance-based analysis and sorting of sperm cells.

Lab on a chip·2016
Same author

Microfluidic single sperm entrapment and analysis.

Lab on a chip·2015
Same journal

A two-step centrifugal microfluidic platform for semi-automated IGRA detection of tuberculosis based on chemiluminescence.

The Analyst·2026
Same journal

On-site rapid identification of animal and plant creams <i>via</i> 2D FeB nanozyme-based colorimetric sensors.

The Analyst·2026
Same journal

Sensitive detection of aflatoxin B1 using a dual-mode fluorescent aptasensor based on cascade signal amplification.

The Analyst·2026
Same journal

Deep learning-enabled microfluidic digital PCR platform for efficient seven-color quantification.

The Analyst·2026
Same journal

Monitoring food spoilage biogenic amines utilizing a blue-emitting fluorescent ionic liquid.

The Analyst·2026
Same journal

Correction: Regeneration-on-a-chip: a planarian microfluidic device enabling automated cultivation, individual tracking and <i>in vivo</i> imaging for regeneration study.

The Analyst·2026
See all related articles

This study introduces a novel electrochemical sensor for glucose measurement using an engineered metal-oxide-semiconductor field-effect transistor (EMOSFET). The device demonstrates enhanced sensitivity and a tunable detection limit for accurate glucose monitoring.

Area of Science:

  • Electrochemistry
  • Biosensors
  • Materials Science

Background:

  • Accurate glucose monitoring is crucial for diabetes management.
  • Existing glucose sensors face challenges in sensitivity and detection limits.
  • Field-effect transistors offer a promising platform for biosensing applications.

Purpose of the Study:

  • To develop and characterize a novel electrochemical sensor for glucose detection.
  • To investigate the performance of an EMOSFET-based sensor utilizing immobilized enzymes.
  • To explore the impact of a "constant current potentiometry" mode on sensor sensitivity.

Main Methods:

  • Immobilization of glucose oxidase and horseradish peroxidase onto an EMOSFET gate.
  • Utilizing a redox reaction between glucose, enzymes, and the gate material to generate a measurable signal.

Related Experiment Videos

  • Employing "constant current potentiometry" to enhance sensor performance.
  • Characterizing sensor response based on changes in threshold voltage.

    • Main Results:

    • The EMOSFET-based sensor successfully measured glucose concentrations potentiometrically.
    • The "constant current potentiometry" mode significantly increased sensor sensitivity beyond the Nernstian limit.
    • The sensor's detection limit was tunable by adjusting applied current and enzyme concentration.
    • The device demonstrated potential for sensitive and selective glucose detection.

    Conclusions:

    • The developed EMOSFET sensor provides a sensitive and tunable platform for glucose measurement.
    • Enzyme immobilization and potentiometric detection offer a viable approach for electrochemical biosensing.
    • The "constant current potentiometry" method enhances the analytical performance of FET-based biosensors.
    • This technology holds promise for improved glucose monitoring systems.