Conjunctival ulceration following triamcinolone injection.

Area of Science:

• Ophthalmology
• Dermatology

Background:

• Corticosteroids like triamcinolone acetonide are frequently used for periocular conditions.
• Periocular injections aim to deliver medication directly to the target area.

Observation:

• Three patients developed conjunctival ulceration following periocular triamcinolone acetonide injections.
• The triamcinolone acetonide was deposited in the subtenon's or subconjunctival space.
• Cultures from the ulcer edges were negative, suggesting a non-infectious etiology.

Findings:

• Conjunctival ulceration is a potential complication of periocular triamcinolone acetonide administration.
• The majority of the injected triamcinolone extruded from the site.
• The conjunctival ulcers healed with minimal scarring in the observed cases.

Implications:

• Clinicians should be aware of conjunctival ulceration as a possible adverse event.
• Careful injection technique may be necessary to minimize this risk.
• Understanding this complication aids in patient counseling and management.