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Updated: Sep 20, 2026

Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis
Published on: February 6, 2021
Post traumatic polymicrobial endophthalmitis, including Neisseria subflava
Shobha Sharma1, Norman A Saffra, Edward K Chapnick
1Division of Infectious Diseases, Department of Medicine, Maimonides Medical Center, Brooklyn, New York 11219, USA. SShoba@msn.com
Design:
To report the second known case of post-traumatic endophthalmitis caused by Neisseria subflava.
Design:
Interventional case report.
Methods:
A two-year-old child with post-traumatic corneal laceration and uveal prolapse required medical and surgical therapy for endophthalmitis caused by multiple organisms including N. subflava.
Results:
After aggressive therapy, patient had a favorable outcome without vision compromise.
Conclusions:
As there is still not a standard protocol for therapy for post-traumatic endopthalmitis, we recommend the use of broad-spectrum antibiotics via intravitreal, intravenous, and topical routes. Consideration of typical and unusual bacteria that have been reported to cause endopthalmitis, as well as the source of injury, should guide antibiotic choice.
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