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Identifying physician-recognized depression from administrative data: consequences for quality measurement
Claire M Spettell1, Terry C Wall, Jeroan Allison
1Health Informatics/USQA, Blue Bell, PA 19422, USA.
Insights
Identifying depression in administrative data is challenging. Two algorithms showed varying accuracy, with one having a high false positive rate, raising concerns for quality reporting.
Area of Science:
- Health Services Research
- Medical Informatics
- Psychiatry
Background:
- Administrative data is crucial for healthcare quality measurement, including systems like the Health Plan Employer Data and Information Set (HEDIS).
- Accurate identification of patients with depression from administrative data is limited by several factors.
Purpose of the Study:
- To investigate and compare two algorithms for identifying physician-recognized depression using administrative data.
- To assess the performance of these algorithms in terms of sensitivity, specificity, and positive predictive value.
Main Methods:
- Two algorithms were developed to identify depression: Algorithm 1 required two criteria (depression diagnosis or antidepressant claim), while Algorithm 2 added a mandatory depression diagnosis.
- The study utilized data from a large managed care organization, analyzing member panels enrolled throughout 1997.
- Medical records were reviewed for a subset of patients, and large patient cohorts were identified based on each algorithm.
Main Results:
- Algorithm 1 demonstrated higher sensitivity (95%) and positive predictive value (49%), while Algorithm 2 showed higher specificity (88%) and a better positive predictive value (60%).
- Algorithm 2 identified patients with higher rates of follow-up visits and appropriate antidepressant dosing compared to Algorithm 1.
- Both algorithms exhibited significant false positive rates, impacting the reliability of depression identification.
Conclusions:
- The construction of the denominator significantly influences quality metrics derived from administrative data.
- High false positive rates in both algorithms raise concerns regarding the interpretation of depression quality reports based on administrative data.
- Further research is needed to refine methods for accurate depression identification in administrative datasets.
Background:
Multiple factors limit identification of patients with depression from administrative data. However, administrative data drives many quality measurement systems, including the Health Plan Employer Data and Information Set (HEDIS).
Methods:
We investigated two algorithms for identification of physician-recognized depression. The study sample was drawn from primary care physician member panels of a large managed care organization. All members were continuously enrolled between January 1 and December 31, 1997. Algorithm 1 required at least two criteria in any combination: (1) an outpatient diagnosis of depression or (2) a pharmacy claim for an antidepressant Algorithm 2 included the same criteria as algorithm 1, but required a diagnosis of depression for all patients. With algorithm 1, we identified the medical records of a stratified, random subset of patients with and without depression (n = 465). We also identified patients of primary care physicians with a minimum of 10 depressed members by algorithm 1 (n = 32,819) and algorithm 2 (n = 6,837).
Results:
The sensitivity, specificity, and positive predictive values were: Algorithm 1: 95 percent, 65 percent, 49 percent; Algorithm 2: 52 percent, 88 percent, 60 percent. Compared to algorithm 1, profiles from algorithm 2 revealed higher rates of follow-up visits (43 percent, 55 percent) and appropriate antidepressant dosage acutely (82 percent, 90 percent) and chronically (83 percent, 91 percent) (p < 0.05 for all).
Conclusions:
Both algorithms had high false positive rates. Denominator construction (algorithm 1 versus 2) contributed significantly to variability in measured quality. Our findings raise concern about interpreting depression quality reports based upon administrative data.
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