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Updated: Sep 20, 2026

Palladium N-Heterocyclic Carbene Complexes: Synthesis from Benzimidazolium Salts and Catalytic Activity in Carbon-carbon Bond-forming Reactions
Published on: July 30, 2017
Palladium-catalyzed aerobic oxidative kinetic resolution of alcohols with an achiral exogenous base
Sunil K Mandal1, Matthew S Sigman
1Department of Chemistry, University of Utah, 315 South 1400 East, Salt Lake City, Utah 84112-8500, USA.
Abstract:
Substitution of exogenous (-)-sparteine for a more practical achiral base in the aerobic oxidative kinetic resolution of secondary alcohols is described. Carbonate bases are the most effective of those screened and allow for effective kinetic resolution of benzylic, allylic, and aliphatic substrates. The procedure was also successfully extended to the oxidative desymmetrization of meso diols.
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