Related Experiment Video
Updated: Sep 20, 2026

Assays for the Specific Growth Rate and Cell-binding Ability of Rotavirus
Published on: January 28, 2019
Hospitalization of childhood rotavirus infection from Kuala Lumpur, Malaysia
W S Lee1, P D Veerasingam, A Y T Goh
1Departments of Paediatrics, University of Malaya Medical Center, Kuala Lumpur, Malaysia. leews@um.edu.my
Insights
Rotavirus gastroenteritis is a significant cause of hospital admissions for children with diarrhea in Malaysia. This study highlights its prevalence and common symptoms in young children.
Area of Science:
- Pediatrics
- Infectious Diseases
- Epidemiology
Background:
- Rotavirus is a leading cause of severe diarrheal disease in infants and young children globally.
- Understanding the local epidemiology of rotavirus gastroenteritis is crucial for public health interventions in developing countries.
Purpose of the Study:
- To investigate the epidemiology of rotavirus gastroenteritis in children admitted to an urban hospital in Malaysia.
- To identify the incidence, age distribution, and seasonal patterns of rotavirus infections.
Main Methods:
- A retrospective review of pediatric admissions for acute gastroenteritis at the University of Malaya Medical Centre from 1996 to 1999.
- Analysis of stool samples for rotavirus detection in children with acute diarrhea.
Main Results:
- Rotavirus was detected in 24% of stool samples from children with acute diarrhea, accounting for 1.6% of all pediatric admissions annually.
- The majority of rotavirus cases (72%) occurred in children under two years of age.
- Peak incidence was observed between January-March and September-October, with dehydration being a common complication.
Conclusions:
- Rotavirus gastroenteritis is a frequent reason for pediatric hospitalizations in urban Malaysia.
- The findings underscore the importance of rotavirus surveillance and potential vaccination strategies in the region.
Aim:
To determine the epidemiology of rotavirus gastroenteritis in children admitted to an urban hospital in a developing country from South-East Asia.
Methods:
Retrospective review of cases of acute gastroenteritis admitted to the children's ward of the University of Malaya Medical Centre, Kuala Lumpur, Malaysia, between 1996 and 1999.
Results:
During the study period, 333 cases (24%) of 1362 stool samples, obtained from children admitted with acute diarrhoea, were positive for rotavirus. Acute gastroenteritis constituted 8.2%, and rotavirus infection 1.6% of all the paediatric admissions each year. Of the 271 cases analysed, 72% of the affected population were less than 2 years of age. Peak incidence of admissions was between January to March, and September to October. Dehydration was common (92%) but electrolyte disturbances, lactose intolerance (5.2%), prolonged diarrhoea (2.6%) and cow's milk protein intolerance was uncommon. No deaths were recorded.
Conclusions:
Rotavirus infection was a common cause of childhood diarrhoea that required hospital admission in an urban setting in Malaysia.
Related Concept Videos
Poliomyelitis
Respiratory Syncytial Virus Disease
Bacterial Gastroenteritis
Cholera
