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A framework and case study for exposure assessment in the Voluntary Children's Chemical Evaluation Program
Richard Reiss1, Elizabeth L Anderson, James Lape
1Sciences International, Inc., Alexandria, VA, USA.
Risk Analysis : an Official Publication of the Society for Risk Analysis
|September 13, 2003
Summary
This study introduces a framework for chemical exposure assessments, focusing on children under the U.S. EPA's Voluntary Children's Chemical Evaluation Program (VCCEP). It streamlines evaluating exposure pathways for safer chemical management.
Area of Science:
- Environmental Health
- Toxicology
- Risk Assessment
Background:
- The U.S. EPA's Voluntary Children's Chemical Evaluation Program (VCCEP) requires comprehensive chemical assessments.
- Evaluating all potential exposure pathways for chemicals is a complex challenge for assessors.
Purpose of the Study:
- To present a conceptual framework for conducting exposure assessments within the VCCEP.
- To provide guidance for managing the complex process of identifying and evaluating chemical exposure pathways.
Main Methods:
- Development of a framework to interpret exposure information and identify relevant pathways.
- Utilizing a tiered approach, starting with screening-level methods and progressing to refined assessments.
- Application of the framework through a hypothetical case study.
Main Results:
- The framework aids in developing plausible exposure pathway lists and eliminating negligible concerns.
- It guides the efficient use of tiered assessment strategies.
- The case study illustrates the practical application of the framework's concepts.
Conclusions:
- The proposed framework simplifies and enhances the process of chemical exposure assessment for VCCEP.
- It supports a systematic and efficient evaluation of chemical risks to children.