Jove
Visualize
Contact Us

Related Concept Videos

Pedigree Analysis01:35

Pedigree Analysis

19.1K
No description available
19.1K
Pedigree Analysis01:35

Pedigree Analysis

90.8K
Overview
90.8K
Probability Laws01:49

Probability Laws

44.9K
Overview
44.9K
Punnett Squares01:00

Punnett Squares

127.7K
Overview
127.7K
Punnett Squares01:00

Punnett Squares

15.3K
No description available
15.3K
The Ratio of X Chromosome to Autosomes02:45

The Ratio of X Chromosome to Autosomes

10.1K
In most organisms, sex is determined by the ratio of X and Y chromosomes. However, in some organisms, such as Drosophila and C.elegans, sex is determined by the ratio of the number of X chromosomes to the number of sets of autosomes. The Y chromosome in Drosophila is active but does not determine sex. It contains genes responsible for the production of sperms in adult flies.  
Normal male Drosophila has a ratio of one X chromosome to two sets of autosomes. In contrast, normal female...
10.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Sample size determination for jointly testing a cause-specific hazard and the all-cause hazard in the presence of competing risks.

Statistics in medicine·2017
Same author

Efficient Monte Carlo evaluation of resampling-based hypothesis tests with applications to genetic epidemiology.

Statistical methods in medical research·2016
Same author

Identifying contributors of two-person DNA mixtures by familial database search.

International journal of legal medicine·2012
Same author

The evidentiary values of "cold hits" in a DNA database search on two-person mixture.

Science & justice : journal of the Forensic Science Society·2011
Same author

Detection of parent-of-origin effects using general pedigree data.

Genetic epidemiology·2009
Same author

Evaluation of DNA mixtures from database search.

Biometrics·2009
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Mar 28, 2026

Simultaneous Assessment of Kinship, Division Number, and Phenotype via Flow Cytometry for Hematopoietic Stem and Progenitor Cells
10:20

Simultaneous Assessment of Kinship, Division Number, and Phenotype via Flow Cytometry for Hematopoietic Stem and Progenitor Cells

Published on: March 24, 2023

2.3K

User-friendly programs for easy calculations in paternity testing and kinship determinations.

Wing K Fung1

  • 1Department of Statistics and Actuarial Science, University of Hong Kong, Pokfulam Road, Hong Kong, China. wingfung@hku.hk

Forensic Science International
|September 13, 2003
PubMed
Summary

Four new computer programs simplify likelihood ratio calculations for paternity and kinship testing. These tools utilize Bayes Theorem and pedigree analysis for accurate genetic relationship assessments.

More Related Videos

Microsatellite DNA Genotyping and Flow Cytometry Ploidy Analyses of Formalin-fixed Paraffin-embedded Hydatidiform Molar Tissues
11:54

Microsatellite DNA Genotyping and Flow Cytometry Ploidy Analyses of Formalin-fixed Paraffin-embedded Hydatidiform Molar Tissues

Published on: October 20, 2019

9.9K
Digital Polymerase Chain Reaction Assay for the Genetic Variation in a Sporadic Familial Adenomatous Polyposis Patient Using the Chip-in-a-tube Format
05:58

Digital Polymerase Chain Reaction Assay for the Genetic Variation in a Sporadic Familial Adenomatous Polyposis Patient Using the Chip-in-a-tube Format

Published on: August 20, 2018

11.5K

Related Experiment Videos

Last Updated: Mar 28, 2026

Simultaneous Assessment of Kinship, Division Number, and Phenotype via Flow Cytometry for Hematopoietic Stem and Progenitor Cells
10:20

Simultaneous Assessment of Kinship, Division Number, and Phenotype via Flow Cytometry for Hematopoietic Stem and Progenitor Cells

Published on: March 24, 2023

2.3K
Microsatellite DNA Genotyping and Flow Cytometry Ploidy Analyses of Formalin-fixed Paraffin-embedded Hydatidiform Molar Tissues
11:54

Microsatellite DNA Genotyping and Flow Cytometry Ploidy Analyses of Formalin-fixed Paraffin-embedded Hydatidiform Molar Tissues

Published on: October 20, 2019

9.9K
Digital Polymerase Chain Reaction Assay for the Genetic Variation in a Sporadic Familial Adenomatous Polyposis Patient Using the Chip-in-a-tube Format
05:58

Digital Polymerase Chain Reaction Assay for the Genetic Variation in a Sporadic Familial Adenomatous Polyposis Patient Using the Chip-in-a-tube Format

Published on: August 20, 2018

11.5K

Area of Science:

  • Forensic Genetics
  • Computational Biology
  • Biostatistics

Background:

  • Accurate likelihood ratio (LR) calculations are crucial for genetic relationship testing.
  • Existing methods for LR computation can be complex and time-consuming.
  • The need for user-friendly and efficient software tools in this field is evident.

Purpose of the Study:

  • To develop and present four computer programs for simplified LR calculations.
  • To facilitate paternity testing and kinship determination using computational methods.
  • To provide accessible software based on established probability theories.

Main Methods:

  • Development of four distinct computer programs.
  • Application of Bayes Theorem, conditional probability, and pedigree analysis principles.
  • Utilization of computer enumeration for calculation efficiency.
  • Implementation of a user-friendly pull-down manual interface.

Main Results:

  • Successful creation of four functional computer programs for LR calculations.
  • Demonstrated ease of use and efficient computation of LRs.
  • Capability for users to save and verify calculation results.
  • Wide applicability of the software in genetic relationship testing.

Conclusions:

  • The developed software offers a significant improvement in the ease and efficiency of LR calculations for genetic testing.
  • These programs provide a valuable tool for forensic scientists and geneticists.
  • The user-friendly design enhances accessibility and practical application in paternity and kinship analyses.