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An Allelotyping PCR for Identifying Salmonella enterica serovars Enteritidis, Hadar, Heidelberg, and Typhimurium
Published on: July 22, 2011
Salmonella-induced enteritis. Clinical, serotypes and treatment
F Ramadan1, A G Unni, R Hablas
1Medical Department, Royal Commission Hospital, Yanbu, Kingdom of Saudi Arabia.
The Journal of the Egyptian Public Health Association
|January 1, 1992
Summary
Salmonella enteritis is a significant health issue, especially in developing nations. This study identified common Salmonella serotypes in Yanbu, Saudi Arabia, finding S. typhimurium most prevalent and norfloxacin effective against resistant strains.
Area of Science:
- Microbiology
- Infectious Diseases
- Public Health
Background:
- Salmonella enteritis causes significant morbidity and mortality globally, particularly in developing countries.
- Salmonella serotype prevalence varies geographically and temporally.
- Understanding local Salmonella epidemiology is crucial for effective public health interventions.
Purpose of the Study:
- To determine the prevalence of different Salmonella serotypes in the Yanbu area, Saudi Arabia.
- To identify the most common Salmonella serotypes causing gastroenteritis in the region.
- To evaluate the antibiotic susceptibility patterns of isolated Salmonella strains.
Main Methods:
- Analysis of 136 stool cultures from patients with gastroenteritis at Royal Commission Hospital, Yanbu.
- Identification and serotyping of Salmonella isolates.
- Antibiogram testing to assess susceptibility to various antibiotics, including norfloxacin.
Main Results:
- Thirty-one Salmonella isolates were identified, belonging to 15 different serotypes, all of the gastroenteric, diarrhoeagenic, non-invasive group.
- The most common serotype was Salmonella typhimurium (45.16%), followed by Salmonella enteritidis (9.62%) and Salmonella virchow (6.46%).
- All isolates were sensitive to norfloxacin, with varying resistance to chloramphenicol, ampicillin, and trimethoprim.
Conclusions:
- Salmonella typhimurium is the predominant serotype causing enteritis in the Yanbu area.
- Norfloxacin demonstrated high efficacy against resistant Salmonella strains with a favorable safety profile.
- These findings highlight the importance of local surveillance of Salmonella serotypes and antibiotic resistance patterns.
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