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[Comparison between pre-thickened and home-thickened formulas in gastroesophageal reflux treatement]
Francisco J Penna1, Rocksane C Norton, Anfrisina S T Carvalho
1Faculdade de Medicina, Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, MG, Brazil.
Insights
Both pre-thickened and homemade infant formulas effectively manage gastroesophageal reflux (GER) symptoms in infants. Neither method showed a significant difference in reducing regurgitation and vomiting in this study.
Area of Science:
- Pediatrics
- Gastroenterology
- Nutrition
Background:
- Gastroesophageal reflux (GER) is common in infants, often causing regurgitation and vomiting.
- Management strategies include dietary modifications, such as thickened formulas.
- Comparing commercially available pre-thickened formulas with homemade thickened formulas is crucial for clinical guidance.
Purpose of the Study:
- To compare the efficacy of a pre-thickened infant formula (Nan AR) against a conventional homemade thickened formula.
- To assess the reduction in regurgitation and vomiting in infants diagnosed with GER.
Main Methods:
- A study involving 100 infants under 12 months not exclusively breastfed.
- Infants were divided into two groups: 48 received conventional formula thickened with starch, and 52 received a pre-thickened infant formula.
- Outcomes measured included improvement or cure of GER symptoms.
Main Results:
- No statistically significant difference was observed between the pre-thickened formula group and the homemade thickened formula group.
- Both treatment approaches demonstrated effectiveness in managing infant GER symptoms.
Conclusions:
- Pre-thickened infant formulas and homemade thickened formulas exhibit comparable efficacy.
- Both methods are effective in the clinical management of gastroesophageal reflux in pediatric patients.
Objective:
The purpose of this study was to compare the effectiveness of a pre-thickened infant formula (Nan AR) with a conventional homemade formula in the reduction of regurgitation and vomiting in infants with gastroesophageal reflux.\par
Methods:
A hundred children, under 12 months, not exclusively breast feeding, were select for the study. Forty-eight were treated with conventional formula with starch and 52 with pre-thickened infant formula.\par
Results:
There was no statistically significant difference between the two groups in the improvement or cure of symptoms, each treatment having been effective.\par
Conclusion:
Thickened formulas, pre-thickened or home-thickened, have shown the same efficacy in the management of gastroesophageal reflux in children.