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Updated: Aug 10, 2026
Rapid Evaluation of Toxicity of Chemical Compounds Using Zebrafish Embryos
Published on: August 25, 2019
[Impact of aldicarb and its complex pollution on DNA of zebrafish embryo]
Yang Li1, Qingmin Zhang, Shugui Dai
1College of Environmental Science and Engineering, Nankai University, Tianjin 300071, China. liyan0805@sina.com.cn
Abstract:
This paper deals with the impact of a complex pollution system composed of a very toxic carbamate pesticide, aldicarb and the widely used anionic surfactant, sodium dodecylbenzenesulfonate(SDBS), on DNA of zebrafish (Brachydanio rerio) embryo. The results indicated that DNA damage caused by aldicarb became more serious with its increasing concentration, but single-strand break caused by aldicarb in low concentration and short time could be repaired, and high concentration led to double-strand break which was difficult to repaire. SDBS in certain concentration (20 mg.L-1) could reduce the toxicity of aldicarb in the complex pollution system.
