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Sequencing and chromosomal localization of Fabp6 and an intronless Fabp6 segment in the rat

Anita Bonné1, Claudia Gösele, Maria den Bieman

  • 1Department of Laboratory Animal Science, Faculty of Veterinary Science, Utrecht University, P.O. Box 80166, 3508 TD Utrecht, The Netherlands. A.bonne@antrg.umcn.nl

Molecular Biology Reports
|September 17, 2003
PubMed

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Cis-regulatory Sequences

Cis-regulatory sequences are short fragments of non-coding DNA that are present on the same chromosomes as the genes that they regulate. These fragments serve as binding sites for transcriptional regulators, proteins that are responsible for controlling gene transcription and differential gene expression across cell types in eukaryotes. Cis-regulatory sequences can be close to the gene of interest or thousands of bases away in the DNA sequence; however, those sequences that are further away are...