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Updated: Aug 10, 2026

A Microfluidic Model of Biomimetically Breathing Pulmonary Acinar Airways
Published on: May 9, 2016
Efficient computations of gas transport in the respiratory tree
Jonathan P Whiteley1, David J Gavaghan
1Oxford University, Computing Laboratory, Wolfson Building, Parks Road, Oxford OX1 3QD, UK.
Abstract:
The equation governing the transport of an inert gas in the respiratory tree is a linear PDE. There are several clinical situations where the PDE must be solved on a large number of consecutive breaths and, on each breath, a very small number of linear functionals of this solution evaluated. In this study we show how the solution of a relatively small number of adjoint problems may be used to calculate these linear functionals, thus reducing the volume of computation significantly. This technique may be used with other physical problems.
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