Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Factors affecting gallbladder motility: drugs.

L Marzio1

  • 1Department of Medicine and Ageing, G. d'Annunzio University, Chieti-Pescara, Italy. marzio@unich.it

Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver
|September 17, 2003
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Efficacy of four different moxifloxacin-based triple therapies for first-line H. pylori treatment.

Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·2009
Same author

Effect of baclofen on oesophageal motility and transient lower oesophageal sphincter relaxations in GORD patients: a 48-h manometric study.

Neurogastroenterology and motility·2008
Same author

Effect of the 5-HT3 receptor antagonist, ondansetron, on gastric size in dyspeptic patients with impaired gastric accommodation.

Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·2008
Same author

Peppermint oil (Mintoil) in the treatment of irritable bowel syndrome: a prospective double blind placebo-controlled randomized trial.

Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·2007
Same author

Effect of an acute intraluminal administration of capsaicin on oesophageal motor pattern in GORD patients with ineffective oesophageal motility.

Neurogastroenterology and motility·2006
Same author

Effects of combining extracts (from propolis or Zingiber officinale) with clarithromycin on Helicobacter pylori.

Phytotherapy research : PTR·2006
Same journal

Toward safer rechallenge after severe immune-mediated hepatotoxicity: the need for dynamic and mechanism-informed risk stratification.

Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·2026
Same journal

Double immunohistochemistry to detect transglutaminase 2-IgA deposits in celiac children: a multicentre study.

Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·2026
Same journal

Effectiveness and safety of mirikizumab in multirefractory ulcerative colitis: analysis from a real-world cohort.

Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·2026
Same journal

Novel approaches to liquid biopsy in pancreatic cancer.

Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·2026
Same journal

GLP-1 receptor agonists in pediatric obesity.

Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·2026
Same journal

An unusual gastric mass in a patient with human immunodeficiency virus infection.

Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·2026
See all related articles

This study reviews medications that affect gallbladder contraction. Drugs like cholecystokinin stimulate contraction, while atropine and somatostatin inhibit it, offering therapeutic options.

Area of Science:

  • Gastroenterology
  • Pharmacology

Background:

  • The gallbladder plays a crucial role in digestion by storing and releasing bile.
  • Understanding agents that modulate gallbladder function is essential for managing various gastrointestinal disorders.

Purpose of the Study:

  • To comprehensively review drugs and medications that influence gallbladder contraction and basal tone in humans.
  • To categorize agents based on their stimulatory or inhibitory effects on gallbladder motility.

Main Methods:

  • Literature review of pharmacological agents affecting gallbladder function.
  • Categorization of drugs based on their mechanisms of action (hormonal, cholinomimetic, etc.).

Main Results:

  • Stimulation of gallbladder contraction can be achieved with synthetic hormones (cholecystokinin, caerulein, motilin), cholinomimetics (bethanecol, prostigmine), and erythromycin.

Related Experiment Videos

  • Inhibition of gallbladder contraction is associated with atropine, somatostatin, nifedipine, and progesterone.
  • Certain drugs like trimebutine, loperamide, and ondansetron may negatively impact gallbladder contraction.

    • Conclusions:

    • A diverse range of pharmacological agents can modulate gallbladder contraction and basal tone.
    • These agents offer potential therapeutic strategies for conditions involving gallbladder dysfunction.