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Congenital heart defects: 15 years of experience of the Emilia-Romagna Registry (Italy)

E Calzolari1, G Garani, G Cocchi

  • 1Medical Genetic Section, Department of Experimental and Diagnostic Medicine, University of Ferrara, Italy. cls@unife.it

European Journal of Epidemiology
|September 17, 2003
PubMed

Insights

This study analyzed congenital heart defects (CHDs) in the Emilia-Romagna Region, identifying patient groups for genetic research. Epidemiological data were collected to aid public health surveillance of CHDs.

Area of Science:

  • Pediatric Cardiology
  • Medical Genetics
  • Public Health Surveillance

Background:

  • Congenital heart defects (CHDs) represent a significant global health concern.
  • Understanding the epidemiology of CHDs is crucial for targeted interventions and research.

Purpose of the Study:

  • To collect and assess data on CHD occurrence in the Emilia-Romagna Region.
  • To establish a homogeneous patient cohort for etiological and genetic investigations.
  • To provide epidemiological insights for public health surveillance.

Main Methods:

  • Analysis of 1549 stillborn and live-born infants with CHDs from 330,017 consecutive births.
  • Data collection focused on CHD types, sex ratio, extracardiac anomalies, and chromosomal abnormalities.

Main Results:

  • The study determined the frequency and types of CHDs within the region.
  • Associated extracardiac and chromosomal anomalies were identified.
  • The impact of prenatal diagnosis on CHD prevalence was minimal during the study period.

Conclusions:

  • The research generated essential epidemiological data for CHD public health surveillance in Emilia-Romagna.
  • A standardized nationwide system for CHD recording, encompassing ascertainment, diagnostic criteria, and classification, is recommended.
Abstract

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