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Meta-Analysis of the Effectiveness and Safety of Shugan Jieyu Capsules for the Treatment of Insomnia
Published on: February 17, 2023
[Treatment of insomnia in children: pharmacological aspects]
Ma A Idiazábal Alecha1, E Estivill Sancho
1Unidad de Sueño, Institut Universitari Dexeus, Barcelona, España. mariannf@eresmas.com
Insights
Pediatricians often treat childhood sleep disorders with medication, though non-pharmacological approaches like sleep hygiene are preferred. Melatonin shows promise for treating insomnia in children, especially those with neurological conditions.
Area of Science:
- Pediatrics
- Sleep Medicine
- Pharmacology
Context:
- Childhood sleep disorders are a growing concern, with many pediatricians using medication despite limited recommendations for children.
- Established treatments for adult insomnia are often unsuitable for pediatric populations.
- Over half of pediatricians report using medication for childhood sleep issues.
Purpose:
- To review the causes of insomnia in children from birth to school age.
- To discuss and evaluate various therapeutic options for pediatric insomnia.
- To highlight effective treatments for different types of childhood insomnia.
Summary:
- Commonly used hypnotics include benzodiazepines and non-benzodiazepine agents (e.g., imidazopyridine).
- Melatonin, while less studied, appears safe and effective for school-aged children's insomnia.
- Initial management involves assessing sleep and environmental factors, ruling out organic causes, and educating parents on sleep hygiene.
Impact:
- Emphasizes non-pharmacological interventions like sleep hygiene and habit training as first-line treatments.
- Suggests cautious use of pharmacological agents with the lowest effective doses when necessary.
- Identifies melatonin as a potentially valuable and safe option for pediatric insomnia, including in children with neurological disorders.
Abstract:
In the last few years topics related to sleep in children have aroused increased interest. Most hypnotic drugs and sedatives used to treat adult insomnia are not recommended in children. Even so, 56% of pediatricians use medication to treat childhood sleep disorders. We review the different causes of insomnia in children from birth to school age. The various therapeutic options are discussed and the therapeutic methods that have been demonstrated to be most effective in the various types of insomnia. The most frequent hypnotic drugs used in insomnia treatment are benzodiazepines and non-benzodiazepine hypnotics such as imidazopyridine, pyrazolopyrimidine and cyclopyrrolone. Few studies have been published on the use of melatonin in insomnia although several reports suggest that is useful and relatively safe in the treatment of insomnia in school-aged children. In children with insomnia, pediatricians should first of all obtain information about the characteristics of insomnia and the environmental characteristics surrounding the child and his/her family. Once an organic cause has been ruled out, treatment should be based on informing the parents about sleep physiology and on training them in sleep hygiene and the acquisition of sleep habits. When pharmacological treatment is required, it should be carefully selected using the smallest effective doses. Melatonin seems to have a promising future in insomnia treatment in healthy children and in those with neurological disorders.
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