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Updated: Aug 12, 2026

A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia
Published on: August 18, 2015
[Cerebral infarct secondary to carotid artery dissection]
J R Bretón Martínez1, J I Muñoz Bonet, M C Llopis Garrido
1Servicio de Pediatría, Hospital Universitario Dr Peset, Valencia, España. breton_raf@gva.es
Insights
Internal carotid artery dissection can cause ischemic stroke in young patients, often linked to trauma or arterial wall defects. Early diagnosis via imaging and prompt treatment, including anticoagulation or surgery, are crucial for managing this condition.
Area of Science:
- Neurology
- Vascular Medicine
- Pediatric Cardiology
Background:
- Internal carotid artery dissection is a significant cause of ischemic stroke in pediatric and young adult populations.
- Predisposing factors may include trauma or congenital arterial wall abnormalities.
Observation:
- Patients typically present with ipsilateral headache, neck pain, and Horner's syndrome.
- Delayed ischemic symptoms are characteristic of this condition.
Findings:
- Diagnosis is confirmed through various imaging modalities such as ultrasound, Doppler, MRI, MRA, and conventional angiography.
- A case of a 14-year-old boy with internal carotid artery dissection leading to ischemic stroke is presented.
Implications:
- Effective management strategies involve anticoagulation, antiplatelet therapy, and surgical intervention.
- Understanding the presentation and diagnostic methods is key for timely intervention in young stroke patients.
Abstract:
Dissection of the internal carotid artery is an important cause of ischemic stroke in children and young patients. Trauma and/or an underlying structural defect of the arterial wall have been suggested to be predisposing factors. The typical patient presents with ipsilateral headache or neck pain, ipsilateral Horner's syndrome and delayed ischemic symptoms. Diagnosis is given by ultrasound, transcranial Doppler, magnetic resonance imaging, magnetic resonance angiography and conventional angiography. Treatment of this type of injury includes anticoagulation therapy, antiplatelet therapy and surgery. We report a 14-year-old boy with internal carotid artery dissection who presented with ischemic stroke.
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