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Updated: Aug 8, 2026

A Zebrafish Model of Diabetes Mellitus and Metabolic Memory
Published on: February 28, 2013
Recent developments in the treatment of type 2 diabetes mellitus
1Hospital 12 de Octubre, Servicio de Nefrologia, Madrid, Spain. lru00001@teleline.es
Abstract:
The last couple of decades have seen a great improvement in our understanding of risk factors in diabetes. In particular, a number of studies have demonstrated the major harmful role of hypertension in combination with diabetes. In a parallel development, pharmacological developments have greatly increased our ability to control both blood pressure and glycaemic exposure. This review focuses on hypertension as a risk factor and of the role of emerging therapies, in the light of their effects beyond the direct lowering of blood pressure. Agents that interfere with the renin-angiotensin system, particularly angiotensin-receptor blockers, may have particular benefits on end-organs in diabetic patients.
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