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[Gastric consequences of toxicoseptic agression]
Revista De Chirurgie, Oncologie, Radiologie, O.R.L., Oftalmologie, Stomatologie. Chirurgie
|September 1, 1975
Summary
Gastrointestinal secretory and motor functions change dynamically with toxico-septic syndrome stages. Acute phases show hypersecretion and hypomotility, while chronic phases exhibit hyposecretion, normalizing in later stages.
Area of Science:
- Gastroenterology
- Internal Medicine
- Pathophysiology
Background:
- Gastrointestinal disturbances are common in critically ill patients.
- Toxico-septic syndrome can significantly impact physiological functions.
Purpose of the Study:
- To investigate the dynamic changes in gastric secretory and motor functions during toxico-septic syndrome.
- To compare these changes between a control group and patients with toxico-septic syndrome.
Main Methods:
- Comparative study involving two patient groups: a control group (anesthetic-surgical aggression) and a study group (toxico-septic syndrome).
- Assessment of gastric secretory (hydrochloric acid levels) and motor (motility) functions across different stages of the syndrome.
Main Results:
- Acute toxico-septic syndrome is characterized by hypersecretion of hydrochloric acid and gastric hypomotility.
- Chronic stages show insulin- and histamine-resistant acid hyposecretion, with anachlorhydria in 30% of cases.
- Gastric function (motility and secretion) returns to normal during the metabolic inversion phase.
Conclusions:
- Gastric secretory and motor disturbances evolve dynamically with the clinico-biological phases of toxico-septic syndrome.
- Understanding these dynamics is crucial for managing patients with severe infections and metabolic disturbances.