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Spontaneous platelet aggregation in thalassemic children and adolescents
V Laosombat1, M Wongchanchailert, K Kenpitak
1Department of Pediatrics, Faculty of Medicine, Prince of Songkla University, Hat Yai, Thailand 90112.
Abstract:
Spontaneous platelet aggregation was studied in 51 children and adolescents, comprising 30 nonsplenectomized thalassemic patients, 12 splenectomized thalassemic patients and 9 normal children. Spontaneous platelet aggregation was significantly increased in whole blood and platelet-rich plasma of splenectomized thalassemic patients but not in nonsplenectomized cases.