[The pathologic myocardial change caused by intracoronary ethyl alcohol injection and its mechanism]

Intracoronary chemical injection to ablate ventricular tachycardia is a new method. Through experiments in 22 dogs, we studied the pathologic change of the myocardium and its mechanism following intracoronary injection of 96% ethyl alcohol. All dogs receiving ethyl alcohol injection displayed myocardial necrosis, and most of them presented thrombus in the coronary branch. The pathologic change in the acute period may have resulted from direct ethyl alcohol damage, and that in the late period may have resulted from both direct damage and thrombus caused by arterial damage.