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General estimation of relative potency using prior information
1Department of Mathematics and Statistics, University of Guelph, Ontario, Canada.
Journal of Biopharmaceutical Statistics
|January 1, 1992
Abstract:
A general point and interval estimator of the log relative potency is exhibited in closed form, which incorporates prior information on the log relative potency for symmetrical as well as asymmetrical parallel line bioassay. The point estimator turns out to be a weighted average of the usual estimator and the prior mean where the weights are determined by the prior variance.