Microwave thawing of biological materials using a cylindrical rotational mixing system: a calibration model

A cylindrical device is described for placement within a domestic microwave oven, in order to achieve rapid thawing of biological materials, including plasma, located within the cylinder. The device is economical to fabricate within standard workshop facilities. It secures uniform microwave exposure and continuous mixing of material by rotation of the cylinder in two planes, entraining the motion of the oven drive spindle by a very simple system of frictional gears. Data are presented on the accuracy of this system, and on some important points relating to its use both as a calibration model and a research tool. Such research may eventually enable this system to provide a cheap and reliable option for thawing therapeutic materials for clinical use.