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Double monoclonal cryoglobulinemia, glomerulonephritis and lymphoma
C Rollino1, A Dieny, F Le Marc'hadour
1Service de Néphrologie, Centre Hospitalier Universitaire, Grenoble, France.
Nephron
|January 1, 1992
Abstract:
We present a case of monoclonal cryoglobulinemia with double monoclonal component IgA lambda-IgG lambda, without complement activation, membranoproliferative glomerulonephritis (MPGN) with deposits of IgA, IgG and lambda chains and lymphocytic IgA-lambda-chain-secreting lymphoma. This case emphasizes the possibility that double monoclonal cryoglobulins could behave differently compared to type I cryoglobulins, determining a MPGN-like type II cryoglobulins do, but without activating the complement cascade.