[The mitotic regimen of breast cancer in men]

Mitotic regimen of tumor was studied in 75 male and 50 female patients with breast cancer. Mitotic index (9.7 and 14.3%, respectively) and number of pathologic mitoses (28 and 25%) did not differ significantly between the two groups. However, retardation of chromosome movement in meta-, ana- and telophase was 3 times more frequent in males. This suggests that breast carcinoma in males tends to become more aneuploid than in females. The latter reflects the rate of tumor progression. Clinically, breast cancer in males is characterized by rapid growth, early dissemination and resistance to treatment.