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Nonfunctioning adrenocortical carcinoma.

S M Lele1, B V Mittal, I M Vora

  • 1Dept of Pathology, Seth GS Medical College, Parel, Bombay, Maharashtra.

Journal of Postgraduate Medicine
|July 1, 1992
PubMed
Summary
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Adrenocortical carcinoma, a rare cancer, was diagnosed in a patient presenting with flank swelling and pain. Surgical removal and histopathology confirmed the diagnosis, with no signs of metastasis.

Area of Science:

  • Oncology
  • Pathology

Background:

  • Adrenocortical carcinoma is a rare malignancy of the adrenal gland.
  • Early diagnosis and treatment are crucial for patient outcomes.

Observation:

  • A patient presented with left flank swelling, pain, weakness, and loss of appetite.
  • Ultrasonography identified a left retroperitoneal mass.
  • Radical surgery was performed, involving removal of the left kidney and spleen.

Findings:

  • Histopathological examination confirmed adrenocortical carcinoma.
  • The tumor cells exhibited a specific arrangement in columns and cords within a fibrovascular stroma.
  • The Hough criteria score was 2.97, indicating malignancy.
  • No evidence of metastasis was detected in the resected tissue.

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Implications:

  • This case highlights the importance of considering rare diagnoses in patients with non-specific symptoms.
  • Radical surgical resection is a primary treatment modality for localized adrenocortical carcinoma.
  • Accurate histopathological evaluation is essential for definitive diagnosis and staging.